Professional Biomimetic Skincare

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Professional biomimetic skincare

Healthy skin starts with a strong barrier.

Discover professional-grade barrier care with Enspri Sheer Ceramide. Formulated with skin-compatible lipids to help lock in moisture and support a healthier-looking skin barrier.

Shop Sheer Ceramide Explore the science

★★★★★ 5.0 — 22 verified reviews

Enspri_Sheer_Ceramide_moisture-locking_protective_serum_bottle_in_a_golden_campaign_scene
Before or After Moisturizer?

Before or after — apply before moisturizer to boost absorption, or after moisturizer to seal moisture in. Both ways work, for different jobs.

SHOP BEST SELLERS

Clinically Advanced. Expert Approved.

Enspri Sheer Ceramide serum bottle with 'Best Seller' and 'LNE & SPA'S BEST' labels on a white background An informational skincare graphic for Enspri Sheer Ceramide with the headline 'Intensive Hydration & Skin Comfort' on a warm beige background. The right side shows a woman in profile with closed eyes and a glowing line along her cheek and jawline.
$49.00
$49.00
Enspri Advance Essentials Peptide Plus Collagen Booster Firming Treatment serum with dropper applicator
$50.00
$50.00
Ultra Collagen Mask in a professional jar and Vital Hydrator in a white pump bottle for home mask treatment for skin elasticity and deep hydration. An informational marketing graphic for Enspri Advanced Essentials skincare, featuring before-and-after redness comparison images labeled D0 and D28, a statistic of 16.97% improvement, and product packaging including a collagen mask kit jar and a hydrator gel bottle.
$119.40
$119.40
Enspri Real Client Results badge featuring professional skincare clients and verified results.

Clinical Performance

Clinically studied results you can trust

Selected Enspri formulations are supported by clinical studies and independent testing, demonstrating measurable improvements in skin hydration, barrier function, and visible skin appearance.

View clinical studies

THE SCIENCE

Measured, not marketed

The Ultra Collagen Mask was evaluated on its own independent clinical study- instrumental measurements, not self-reported glow.

Explore Our Skincare Essentials

SHOP BY CONCERN

Start with what your skin is telling you

Nobody shops for a molecule. Pick the concern that sounds like your skin — each one leads to the product built for it.

Golden, translucent serum texture with delicate bubbles, representing Enspri Sheer Ceramide and its moisture-locking skin barrier support.

DRY · TIGHT · REACTIVE

Barrier Support

Skin that stings, flakes, or never feels quite moisturized — post-treatment skin included.

Enspri Ultra Collagen Jar and Vital Hydrator Bottle sitting on a product box on a beige background

FINE LINES · LESS FIRM

Firmness & Glow

Crow's-feet, dullness, and skin that has lost its bounce and suppleness.

Close-up of translucent blue hydrating skincare gel with swirling texture and water droplets, representing daily hydration for dehydrated skin

THIRSTY · UNBALANCED

Daily Hydration

Dehydrated skin that still gets shiny — hydration that balances instead of smothering.

Hand holding a jar of enspri skincare product against a plain background

DULL · TIRED BY MORNING

Overnight Repair

The evening is when skin does its repair work. Give it the richer cream.

SAVE WITH SETS

Complete Your Skincare Routine

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Enspri Anti-Aging Set featuring Peptide Plus Serum, Intense Night Renewal, and Total Eye Boost on a clean, professional background. Enspri Ultra Collagen Jar and Vital Hydrator Bottle sitting on a product box on a beige background
$194.50
$216.20 $194.50
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Enspri Barrier Repair Set featuring Peptide Plus serum, Sheer Ceramide moisture-locking serum, and Intense Night Renewal repair cream to soothe, hydrate, and restore the skin's natural protective barrier. Enspri Advance Essentials Peptide Plus Collagen Booster Firming Treatment serum with dropper applicator
$150.00
$166.80 $150.00
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Complete Enspri professional skincare collection featuring the full Advanced Essentials line: Ultra Collagen Mask system, Peptide Plus, Sheer Ceramide, Hydra Balance, Intense Night Renewal, and Total Eye Boost for a total skin transformation. Enspri Ultra Collagen Jar and Vital Hydrator Bottle sitting on a product box on a beige background
$350.00
$403.20 $350.00
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Enspri Skincare trio featuring Sheer Ceramide, Hydra Balance moisturizer, and Peptide Plus Serum in professional white and blue airless pump bottle, designed for a complete barrier repair and firming routine. Skincare bottle with silver cap and 'enspri' branding on a white background, featuring an LNE-SPA-Best-product-2018-award-badge.
$148.00
$164.80 $148.00

  • Professional Biomimetic Skincare
  • Trusted by Skincare Professionals for 20+ Years
  • Secure Checkout
FOR SKINCARE PROFESSIONALS

Built for the Treatment Room

Professional skincare deserves professional support. Explore Enspri's backbar products, exclusive pricing, and skincare education.

  • Professional Backbar Sizes — Products designed for treatment-room use.
  • Professional Pricing — Exclusive pricing for approved professional accounts.
  • Pro Tips & Education — Skincare guidance and professional insights from the Enspri blog.
Open a Pro Account Explore Pro Tips
Licensed esthetician Jacqueline DiCicco standing beside Enspri professional biomimetic skincare products in a medical spa treatment room.
REAL PEOPLE. REAL RESULTS.

Loved by Clients. Trusted by Experts.

From the show floor at ICES to treatment rooms across the country — Enspri in real hands, not stock photos.

Hands photographed during an Enspri Ultra Collagen treatment demonstration at ICES Long Beach
Hands-on at ICES Long Beach
Enspri skincare products featured in professional aesthetician content
Featured on @enspri_usa
Enspri skincare display and attendee at the ICES Long Beach trade show
At the Enspri Booth — ICES

ENSPRI IN ACTION

Real Results

See Enspri in real treatment rooms, professional demonstrations, and skincare routines.

Individual results vary.